LC-MS & Bioanalysis
How Modern High-Resolution LC-MS and DIA Are Revolutionizing Proteomics
From Data Generation to Data Confidence In today’s rapidly evolving life sciences landscape, high-resolution LC-MS proteomics is shifting from a discovery-oriented technique to a quantitative, decision-enabling platform. This transition is being driven by advances in instrumentation, acquisition strategies, and data analysis approaches that collectively address long-standing challenges in sensitivity, reproducibility, and depth…
Read More
Trace Impurity Analysis for Risk Reduction in Medical Device Development
Why Trace Impurities Matter Early in Development Trace impurities are still too often treated as a late-stage requirement tied to regulatory submission. In medical device development, they are more accurately an early signal of how materials and processes will perform under real conditions. These impurities are small, unintended chemical substances…
Read More
Strengthening Proteomics Capabilities with the Vanquish Neo Nano-LC
In high-resolution proteomics, sensitivity alone is not enough. Advances in proteomics increasingly demand instruments capable of detecting low-abundance proteins with high sensitivity and reproducibility. At iFyber, the addition of the Vanquish™ Neo UHPLC system from Thermo Scientific offers a way to deliver this performance, enabling researchers the opportunity to elevate…
Read More
Nanoflow LC: A Simple Way to Boost Sensitivity in Mass Spectrometry
When you’re trying to detect trace-level peptides or proteins – especially in complex biological matrices like plasma, tissue, or cell lysates – sensitivity becomes everything. In these scenarios, even incremental improvements in signal can be the difference between confident identification and missed data. That’s why nanoflow liquid chromatography (nanoflow LC)…
Read More
iFyber Expands Analytical Capabilities with Launch of Advanced LC-MS Services
Full Release: iFyber Expands Analytical Capabilities with Launch of Advanced LC-MS Services iFyber, LLC, a global preclinical contract research organization (CRO), has announced the expansion of its advanced Liquid Chromatography–Mass Spectrometry (LC-MS) services through the addition of a leading-edge equipment platform and two senior technical experts. These additions expand iFyber’s…
Read More
Immunoaffinity LC-MS: A Transformative Approach to Biomarker Quantification
Liquid chromatography–mass spectrometry (LC-MS) is a cornerstone of biomedical research, drug development, and clinical diagnostics. Immunoaffinity mass spectrometry (IA-MS) enhances LC-MS by combining immunoaffinity enrichment with its high sensitivity and selectivity, overcoming challenges posed by complex biological matrices. IA-MS is a powerful method for biomarker quantification, complementing traditional ligand-binding assays…
Read More
LC-MS: Powering Precision Discovery Across Scientific Frontiers
In an age where precision and speed are essential in research and regulatory environments, Liquid Chromatography–Mass Spectrometry (LC-MS) has become an indispensable tool for scientists. From identifying unknown compounds in complex matrices to elucidating intricate biochemical pathways, LC-MS is redefining what’s possible in modern analytical science. For professionals working in…
Read More