Beyond Standard Preclinical Testing
Custom Science for Problems Without a Standard Protocol
iFyber runs the full range of established preclinical assays, but much of our work starts where a standard test plan runs out. Data that doesn't add up. A problem your team can see but doesn't have the time or in-house expertise to chase down. A project where you're not sure what to test for yet. iFyber works alongside R&D teams in these moments to determine what's actually going on, and what to do about it.
Where Researchers Turn to iFyber
Unexpected Results, Unclear Cause
A study comes back with data that doesn't match expectations — inconsistent performance, a result that contradicts previous work, a spec that fails intermittently for no clear reason. iFyber helps pinpoint whether the issue lies in the material, the method, or the model, and what to test next.
A Recognized Need, Without Bandwidth
Sometimes the challenge is that a team doesn't have the internal expertise or hours available to complete necessary work, whether that’s execution or analysis of results. iFyber's scientists step in to investigate and recommend a path forward.
Unsure Where to Start Testing
Occasionally the challenge isn't a bad result, it's not knowing where to start. iFyber helps define the right questions before determining the assay or method, so time and budget go toward testing that actually moves the project forward.
iFyber’s Approach: Applying Scientific Rigor to New Challenges
Every custom method iFyber develops is grounded in sound statistical and experimental design, so that when a study needs to support regulatory submission, the data holds up.
- Direct, exploratory approaches during early discovery
- Full GLP-compliant validation when data needs to support regulatory review
- Scientists who define the problem clearly before proposing a test, rather than starting from an existing protocol and working backward
A fully scoped study design isn't a prerequisite for reaching out to us. Many iFyber engagements begin with a question. Bring us in when you're stuck, we'll help determine what's possible and how to get there.
Case Study: Building a Better Biofilm Model
The Standard Method
The industry-standard MBEC (Minimum Biofilm Eradication Concentration) assay is widely used for biofilm susceptibility testing, but it supports only a limited range of microorganisms and can produce high result variability.
What iFyber Built
The Bottom-of-the-Plate (BOTP) biofilm assay, a high-throughput alternative that supports a broader range of microorganisms and produces more consistent data.
Where It's Been Applied
Adapted for dental material biofilm testing, evaluating bacterial attachment directly on the material surface rather than relying on less representative planktonic-only methods.
Biofilm Testing for Dental Materials
Read our blog, "Advancing Dental Material Biofilm Testing with High-Throughput In Vitro Assays" to learn more about our approach to biofilm testing for dental materials.