Molecular Biology & Biomarker Analysis
Antibody Stability in Atopic Dermatitis: Why Monoclonal Antibodies Must Be Tested Where They’re Meant to Work
A monoclonal antibody may demonstrate strong target engagement, compelling preclinical efficacy, and favorable early safety signals; and yet experience altered functional durability once it reaches diseased human tissue diseased human tissue. In atopic dermatitis (AD), that risk is not theoretical. As the therapeutic landscape grows more competitive, durability and consistency are emerging as strategic differentiators.…
Read MoreExtracellular Vesicles and Exosomes’ Role in Tissue Regeneration
In regenerative medicine, small biological messengers are making a big impact. Extracellular vesicles (EVs) and a subset of EVs, exosomes, are transforming how scientists think about tissue repair, wound healing, and even skin rejuvenation. These nanoscale carriers of bioactive molecules – proteins, lipids, and nucleic acids – are enabling new cell-free therapies by orchestrating tissue…
Read MoreCytokine Profiling in Surgical Site Healing: What Biomarkers Tell Us
Despite centuries of medical insight and advancement, predicting how a patient will heal after surgery remains challenging. Factors such as age, lifestyle, genetics, comorbidities, and unforeseen complications all influence the healing process. Some patients recover quickly with minimal scarring, while others experience delayed healing, excessive inflammation, or complications like infection and fibrosis. A deeper understanding…
Read MoreMediators of Wound Healing: Cytokines, Growth Factors, and Inflammatory Control
The human body is remarkably adept at repairing itself, both from injuries and infections, and inflammation is an essential part of that process. Activating and controlling the immune response involves many signaling molecules, particularly pro-inflammatory cytokines and anti-inflammatory growth factors. Gaining a better understanding of cytokines and growth factors is essential to developing targeted therapies,…
Read MoreLAMP Assays: Revolutionizing Point-of-Care and At-Home Diagnostics
In the ever-evolving world of medical diagnostics, the need for rapid and accessible testing has never been more crucial. The demand for tests that can be conducted swiftly at the point of care or even in the comfort of our homes has gained significant importance. Loop-Mediated Isothermal Amplification (LAMP) assays are emerging as a transformative force…
Read MoreFrom Clinical Lab Assay to At-Home and Point-of-Care Testing
The world of healthcare is constantly evolving, and recent years have witnessed a significant shift from traditional clinical lab assays to at-home and point-of-care testing. A need for more patient-centric, accessible, and efficient healthcare drives this transformation. Mariely Medina-Rivera, a Research Scientist at iFyber, explains the steps involved in advancing Point of Care (POC) and…
Read MoreChoosing Between Immunoassays and Molecular Assays
Immunoassays and molecular assays are two distinct diagnostic tests used in healthcare and research, each with unique characteristics and applications. Immunoassays are widely used in clinical diagnostics, disease monitoring, and drug testing. They are employed to measure specific proteins or antigens. On the other hand, molecular assays are vital for genetic testing, pathogen detection, and…
Read MoreInflammatory Marker and Growth Factor Publication
New paper titled “Microenvironment Influence of a Novel Bioengineered Wound Product, APIS®: A Preliminary In Vitro Analysis of Inflammatory Marker and Growth Factor Secretion” with our partners at SweetBio, Inc. was published this week. The preliminary in vitro evaluation suggests that the novel bioengineered wound product has the potential to instill balance to the wound microenvironment by…
Read MoreCytokine screening
iFyber has recently started offering a cytokine panel to our clients. Please take a look at our latest whitepaper by Tricia Conti and Nina Bionda. The assay provides a nice screening tool when developing new wound care or regenerative therapies. Learn more here.
Read MoreLab-on-a-Bubble Technology Developed
Lab-on-a-Bubble (LōB) technology developed between iFyber and Snowy Range Instruments shows potential for point-of-care diagnostics…more
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