New paper titled “Microenvironment Influence of a Novel Bioengineered Wound Product, APIS®: A Preliminary In Vitro Analysis of Inflammatory Marker and Growth Factor Secretion” with our partners at SweetBio, Inc. was published this week. The preliminary in vitro evaluation suggests that the novel bioengineered wound product has the potential to instill balance to the wound microenvironment by reducing the MMP-9/TIMP-1 ratio secretion from macrophages and progress previously stalled chronic wounds towards healing by triggering the release of growth factors from fibroblasts.

Isaac Rodriguez, Tricia Conti, Nina Bionda, “Microenvironment Influence of a Novel Bioengineered Wound Product, APIS®: A Preliminary In Vitro Analysis of Inflammatory Marker and Growth Factor Secretion”, International Journal of Biomaterials, vol. 2021, Article ID 6612870, 10 pages, 2021. https://doi.org/10.1155/2021/6612870