Liquid chromatography–mass spectrometry (LC-MS) is a cornerstone of biomedical research, drug development, and clinical diagnostics. Immunoaffinity mass spectrometry (IA-MS) enhances LC-MS by combining immunoaffinity enrichment with its high sensitivity and selectivity, overcoming challenges posed by complex biological matrices. IA-MS is a powerful method for biomarker quantification, complementing traditional ligand-binding assays (LBAs). Gary Schultz, PhD, Director…

Slow-healing wounds, like diabetic foot ulcers, venous leg wounds, and pressure ulcers, frequently turn into long-term battles. When dealing with chronic wounds, treatment can be difficult to target due to a multitude of complicating factors. Diabetes, vascular disease, and immune suppression all reduce the body’s ability to fight infection and repair tissue. Additionally, microbes within…

In a landmark shift that blends scientific progress with environmental responsibility, the United States Pharmacopeia (USP) has endorsed the use of non-animal-derived reagents for endotoxin testing. This decision marks a pivotal advancement in pharmaceutical safety testing while paving the way for a more ethical and sustainable industry standard. For decades, the pharmaceutical and medical device sectors have relied on…

In an age where precision and speed are essential in research and regulatory environments, Liquid Chromatography–Mass Spectrometry (LC-MS) has become an indispensable tool for scientists. From identifying unknown compounds in complex matrices to elucidating intricate biochemical pathways, LC-MS is redefining what’s possible in modern analytical science. For professionals working in therapeutic development, medical devices, combination…