At iFyber, we offer biomarker analysis, working with clients to develop assays for a wide range of biomarkers and sample types, with particular emphasis on the wound care field.

Biomarkers are measurable substances in an organism whose presence can be indicative of a disease state, infection, or environmental exposure. This detectable response can vary based on the specific medical intervention and may give clues regarding disease progression, wound healing, or the physiological side effects of a device or drug treatment.

Using clinical samples, such as wound exudate or tissue, and methods such as ELISA, FACS, qPCR, LAMP, and others, we can identify biomarkers such as:

• Cytokines (e.g., interleukins [ILs] and TNF-α)

• Growth factors (e.g., platelet-derived growth factor [PDGF])

• Matrix metalloproteinases (MMPs)

• Tissue inhibitors of these metalloproteinases (TIMPs)

• MMP/TIMPs ratios

Together with clinical observations, these biomarker measurements can provide clients with a better understanding and more complete picture of how their technology affects the wound healing process.