At iFyber, we work with clients to develop assays for a wide range of biomarkers and sample types, with particular emphasis on the wound care field.

Biomarkers are measurable substances in an organism whose presence can be indicative of a disease state, infection, or environmental exposure. This detectable response can vary based on the specific medical intervention and may give clues regarding disease progression, wound healing, or the physiological side-effects of a device or drug treatment.

Using clinical samples, such as wound exudate or tissue, and methods such as ELISA, FACS, qPCR, LAMP, and others, we can identify biomarkers such as:

• Cytokines (e.g., interleukins [ILs] and TNF-α)
• Growth factors (e.g., platelet-derived growth factor [PDGF])
• Matrix metalloproteinases (MMPs)
• Tissue inhibitors of these metalloproteinases (TIMPs)
• MMP/TIMPs ratios

Together with clinical observations, these biomarker measurements can provide clients with a better understanding and more complete picture of how their technology affects the wound healing process.

Click the links below to learn more about iFyber’s biomarker analysis offerings:

• In vitro
• Biocompatibility Screening
• Lateral Flow Assay Development
• Assessing the Secretome of In vitroDifferentiated Human Macrophages Treated with a Pro-inflammatory Stimulus

Contact us to discuss your biomarker testing needs.